AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2018 Issue 4; New/Revised ICD-10-CM Codes

Plasminogen Deficiency

Code E88.02, Plasminogen deficiency, has been created for the rare genetic disorder caused by a deficiency in plasminogen, an inactive proenzyme that circulates in the blood plasma. Plasminogen deficiency is the absence or dysfunction of plasminogen caused by mutations in the PLG gene. There are two types, Type I and type II. Type I plasminogen deficiency, a quantitative deficiency, is also called hypoplasminogenemia. It is associated with inflamed growths caused by an excess in deposits of fibrin, the active enzyme derived from plasminogen that aids in blood clotting and healing of wound tissues. The deposits form ligneous (wood-like)...

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