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Stevens-Johnson syndrome or toxic epidermal necrolysis

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

A spectrum of severe and life-threatening hypersensitivity disorders affecting skin and mucous membranes, most commonly precipitated by an idiosyncratic reaction to medication. Stevens-Johnson syndrome (SJS) always involves mucosal surfaces but the skin involvement is limited by definition to <10% body surface area (BSA). Toxic epidermal necrolysis (TEN) may sometimes spare mucous membranes but skin involvement is by definition >30% BSA. An intermediate form is recognised in which mucosal involvement is accompanied by skin involvement of 10-30% BSA (SJS-TEN overlap syndrome). All forms result in extensive sloughing and ulceration and carry a significant risk of fatal outcome.

code elsewhere

• Stevens-Johnson syndrome and toxic epidermal necrolysis due to drug  (EH63)

sections/codes in this section (EB13-EB13)

• Stevens-Johnson syndrome  (EB13.0)
• Toxic epidermal necrolysis  (EB13.1)
• Stevens-Johnson and toxic epidermal necrolysis overlap syndrome  (EB13.2)

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