Disorders due to substance use

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2025-01

Disorders due to substance use include disorders that result from a single occasion or repeated use of substances that have psychoactive properties, including certain medications. Disorders related to fourteen classes or groups of psychoactive substances are included. Typically, initial use of these substances produces pleasant or appealing psychoactive effects that are rewarding and reinforcing with repeated use. With continued use, many of the included substances have the capacity to produce dependence. They also have the potential to cause numerous forms of harm, both to mental and physical health. Disorders due to harmful non-medical use of non-psychoactive substances are also included in this grouping.

code elsewhere

• Catatonia induced by substances or medications  (6A41)

sections/codes in this section (6C40-6C4Z)

• Disorders due to use of alcohol  (6C40)
• Disorders due to use of cannabis  (6C41)
• Disorders due to use of synthetic cannabinoids  (6C42)
• Disorders due to use of opioids  (6C43)
• Disorders due to use of sedatives, hypnotics or anxiolytics  (6C44)
• Disorders due to use of cocaine  (6C45)
• Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone  (6C46)
• Disorders due to use of synthetic cathinones  (6C47)
• Disorders due to use of caffeine  (6C48)
• Disorders due to use of hallucinogens  (6C49)
• Disorders due to use of nicotine  (6C4A)
• Disorders due to use of volatile inhalants  (6C4B)
• Disorders due to use of MDMA or related drugs, including MDA  (6C4C)
• Disorders due to use of dissociative drugs including ketamine and phencyclidine [PCP]  (6C4D)
• Disorders due to use of other specified psychoactive substances, including medications  (6C4E)
• Disorders due to use of multiple specified psychoactive substances, including medications  (6C4F)
• Disorders due to use of unknown or unspecified psychoactive substances  (6C4G)
• Disorders due to use of non-psychoactive substances  (6C4H)
• Other specified disorders due to substance use  (6C4Y)
• Disorders due to substance use, unspecified  (6C4Z)

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