8C78 Malignant hyperthermia or hyperpyrexia

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Malignant hyperthermia is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anaesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely in humans, to stresses such as vigorous exercise and heat. May be caused by a mutation in the Ryonadine Receptor 1 gene.

synonyms

• Malignant hyperthermia or hyperpyrexia

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