MF85 Anti-glomerular basement membrane antibody mediated disease

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Anti-GBM mediated glomerulonephritis is an aggressive focal and segmental proliferative glomerular disease characterised by linear staining of the glomerular basement membrane for immunoglobulins, particularly IgG and IgM. Crescentic change is often associated and circulating anti-bodies to glomerular basement membrane are found in active disease. The renal syndrome is often acute nephritis with rapid renal functional decline (rapidly progressive nephritis) and if associated with respiratory involvement (haemoptysis, respiratory failure) the couple is termed “Goodpasture's syndrome”.

inclusions

• Goodpasture syndrome

synonyms

• Anti-glomerular basement membrane antibody mediated disease
• Goodpasture syndrome
• Anti-glomerular basement membrane antibody disease

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