ICD-11 MMS

04 Diseases of the immune system

Certain disorders involving the immune system  (4B20-4B2Y)

4B24 Graft-versus-host disease

4B24.1 Chronic graft-versus-host disease

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01


Chronic graft-versus-host disease (GVHD) presents more than 100 days after engraftment of immunocompetent donor lymphoid cells. It has specific clinical features by which it can be distinguished from acute GVHD. It may arise de novo but frequently follows acute GVHD. Less commonly, it occurs concurrently with acute GVHD. The earlier stages of chronic GVHD are characterised by a widespread lichenoid rash, poikiloderma and involvement of nails and oral mucous membranes. If the disease remains active, progressive sclerosis of the skin and deeper tissues may result in joint contractures, fibrosis of internal organs and severe malabsorption.

postcoordination

Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.

Has severity  - only one may be selected

synonyms

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