ICD-11 MMS

05 Endocrine, nutritional or metabolic diseases

Endocrine diseases  (5A00-5B3Z)

Disorders of the pituitary hormone system  (5A60-5A6Z)

5A60 Hyperfunction of pituitary gland

5A60.0 Acromegaly or pituitary gigantism

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01


Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterised by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The main clinical features are broadened extremities (hands and feet), widened thickened and stubby fingers, and thickened soft tissue. The disease also has rheumatologic, cardiovascular, respiratory and metabolic consequences which determine its prognosis. In the majority of cases, acromegaly is related to a pituitary adenoma, either purely GH-secreting (60%) or mixed. Transsphenoidal surgery is often the first-line treatment. When surgery fails to correct GH/IGF-I hypersecretion, medical treatment with somatostatin analogs and/or radiotherapy can be used.

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postcoordination

Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.

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