von Willebrand factor (vWf).collagen binding activity/von Willebrand factor Ag [Ratio] in Platelet poor plasma by Immunoassay   50378-9

LOINC Code


LOINC code50378-9
namevon Willebrand factor (vWf).collagen binding activity/von Willebrand factor Ag [Ratio] in Platelet poor plasma by Immunoassay
descriptionThis term represents a ratio of two results that are expressed as percentages of normal: the von Willebrand factor.collagen binding activity and the von Willebrand factor antigen concentration, both of which are reported as actual/Normal. The von Willebrand factor (vWF) collagen binding activity to antigen ratio can help distinguish different types of von Willebrand disease (VWD). VWD types 1 and 3 are usually associated with a quantitative decrease in vWF, which would affect both the vWF collagen binding activity as well as vWF antigen concentration, while type 2 is associated with a functional defect in VWF, which would affect the activity but not the amount of antigen present. Therefore, patients with type 2 VWD are likely to have a lower vWF collagen binding activity to antigen ratio (less than 0.5) compared to patients with types 1 or 3 VWD.
statusACTIVE

Fully-Specified Name

componentvon Willebrand factor.collagen binding activity/von Willebrand factor Ag
propertyRatio
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemPPP  =  Platelet poor plasma
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
methodIA  =  Immunoassay:  Encompasses all immunoassays with a few exceptions, including Immune Blot and Immune Fluorescence, which were created based on historic usage.

Additional Names

short namevWF CBA/vWF Ag PPP IA-Rto

Basic Attributes

classCOAG
type1  Laboratory
order vs. observationObservation
formula (readable)(vWF collagen binding activity actual/Normal)/(vWF Ag actual/Normal)
example UCUM units{ratio}
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitratio

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

test rank7393 of 2000 most commonly performed tests by labs in USA
first released
last updated2.73
last change typeMIN  - change to field other than name
change reasonThe EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Related Names

Activ
Actvty
Bind
COAGULATION
EIA
ELFA
ELISA
Enzyme immunoassay
Fac
Fact
Hematology
Heme
IAA
MEIA
Movements
Plas
Platelet poor plasma
Point in time
QNT
Quan
Quant
Quantitative
Random
Ratios
Rto
SUDS
Von will
Vonwillebrand
vWf
vWF CBA
vWF:Ag
vWF:CBA

Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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