53767-0

LOINC Code


LOINC code53767-0
name
descriptionHLA-ABC sequence based typing results in HLA allele assignment for each HLA locus(A,B,C). HLA antigens are the major histocompatibility antigens. HLA Class 1 Sequence-Based typing (HLA-SBT) is used to identify HLA allelic polymorphisms at the level of individual nucleotides using genomic DNA amplified by polymerase chain reaction(PCR). If fewer than two alleles are reported for a locus, the patient can most likely be considered homozygous for that locus, but there is a possibility of an undetected rare allele. HLA-SBT should be used in addition to HLA Class 1 serology and/or low to intermediate resolution molecular typing using either SSP(sequence-specific primers) or SSOPH(sequence-specific oligonucleotide blot hydridization) technology. For clinical purposes, this test should be used as a reflex test to identify unrelated bone marrow donors who are HLA A,B, and C genotypic matches with the intended recipient.
statusACTIVE

Fully-Specified Name

componentHLA-A+B+C SBT
    B  =  Buccal
propertyImp  =  Impression/interpretation of study
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemBld/Tiss
    Bld  =  Whole blood
    Tiss  =  Tissue, unspecified
scaleNom  =  Nominal:  Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody.
methodHigh resolution

Additional Names

short nameA,B; Blood; Genetics; Heredity; Heritable; HLA ANTIGEN; HLA class I; Human Leukocyte Antigen; Impression; Impression/interpretation of study; Impressions; Inherited; Interp; Interpretation; Nominal; Point in time; Random; Sequence based typing; Tissue; Ti

Basic Attributes

classHLA
type1  Laboratory
order vs. observationHLA-A+B+C SBT H

History/Usage

first released
last updated2.73
last change typeMIN  - change to field other than name

Related Names

N

Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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