PhenX - celiac sprue assay protocol 190301   62957-6

LOINC Code


LOINC code62957-6
namePhenX - celiac sprue assay protocol 190301
descriptionThis protocol uses two-step serologic testing of serum to determine the presence of antihuman recombinant tissue transglutaminase (TTG) and endomysial antibody (EMA). When both tests are positive, the subject is notified that they are positive for celiac sprue. The test is most accurate if patients have not been on a gluten-free diet in the weeks leading up to the assay, as a gluten-free diet may cause the serologic assays to normalize in many patients. It is important that the patients screened with this laboratory assay are eating a diet that contains dietary sources of gluten in order for the assay to be most accurate. Sources of dietary gluten include the grains wheat, rye, and barley. The Gastrointestinal Working Group (WG) also recommends performing the immunoglobulin A (IgA) and immunoglobulin G (IgG) antibody tests for more sensitivity. The National Health and Nutrition Examination Survey (NHANES) uses red-top tubes to collect 0.5 ml serum for the antihuman recombinant tissue transglutaminase (TTG)/ endomysial antibody (EMA) bioassay. However, the Gastrointestinal Working Group recommends consulting the laboratory that will perform the bioassay regarding the appropriate collection tubes to use.
statusTRIAL

Fully-Specified Name

componentPhenX - celiac sprue assay protocol 190301
property-
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
system^Patient
scale-
methodPhenX

Additional Names

short nameCeliac sprue assay proto

Basic Attributes

classPANEL.PHENX
type2  Clinical

Panel Components

66177-7History of Hemophilia
66178-5Cancer chemotherapy received in the past 4W or will be received in the next 4W
66504-2Exclusion criteria present [PhenX]
66180-1Was blood drawn [PhenX]
66181-9Was full sample obtained [PhenX]
8251-1Service comment
8251-1Service comment
66208-0Make of the equipment used [Identifier] [PhenX]
74719-6Manufacturer name
66200-7Repeatability of the assay [Ratio] [PhenX]
66201-5Coefficient of variation for the assay
66208-0Make of the equipment used [Identifier] [PhenX]
74719-6Manufacturer name
66200-7Repeatability of the assay [Ratio] [PhenX]
66201-5Coefficient of variation for the assay

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

62949-3PhenX domain - Gastrointestinal

History/Usage

first released
last updated2.67
last change typePANEL  - addition or removal of child elements or change in the conditionality of child elements in the panel or in sub-panels contained by the panel.
change reasonUpdated the PhenX ID from "PhenX." to "PX" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.

Related Names

Pan
Panel
PANEL.PHENX
Panl
Pnl
Point in time
Random

Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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