68466-2
LOINC Code
| LOINC code | 68466-2 | |
|---|---|---|
| name | ||
| description | This term is used for the detection of nuclear Epstein-Barr virus-encoded RNA 1 (EBER1) by in situ hybridization on tissue. Presence of EBER1 indicates a latent EBV infection. EBV encodes two small nuclear RNAs, EBER1 and EBER2, which are the most abundant viral transcripts in latently infected cells. They are non-polyadenylated and thus not translated into protein. Their function is to inhibit interferon-mediated antiviral effects and apoptosis. Since they are expressed at high levels (around a million copies per latently infected cell), they are considered to be an ideal marker of latent EBV infection. In situ hybridization targeting one or both EBERs is used to determine whether a biopsied tumor is EBV-related. | |
| status | ACTIVE | |
Fully-Specified Name | ||
| component | Epstein-Barr virus-encoded RNA 1 | |
| property | PrThr = Present or threshold: The Property PrThr stands for “Presence or Threshold”, meaning either a) the actual presence or absence of an analyte, or b) that the amount of analyte detected is over some predetermined threshold. | |
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | |
| system | Tiss = Tissue, unspecified | |
| scale | Ord = Ordinal: Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive. | |
| method | Probe = DNA Nucleic Acid Probe | |
Additional Names | ||
| short name | DNA NUCLEIC ACID PROBE; DNA probe; EBER; EBER1; EBV; EBV-encoded RNA1; Epstein-Barr virus; Epstn; HHV-4; human herpesvirus 4; i; ID; Infectious Disease; InfectiousDisease; Microbiology; Mono; Mononucleosis; Ordinal; Point in time; PR; QL; Qual; Qualitativ | |
Basic Attributes | ||
| class | MICRO | |
| type | 1 Laboratory | |
| order vs. observation | EBV-encoded RNA | |
History/Usage | ||
| first released | ||
| last updated | 2.63 | |
| last change type | MIN - change to field other than name | |
Related Names | ||
| ||
Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
Thank you for choosing Find-A-Code, please Sign In to remove ads.
Quick, Current, Complete - www.findacode.com