This term was created for (but not limited to) Gen-Probe's Aptima HPV assay (Cat No. 302610) that detects the E6 and E7 polycistronic mRNA from 14 high-risk HPV genotypes (16,18,31,33,35,39,45,51,52,56,58,59,66,and 68) that can lead to cervical cancer. E6/E7 genes in high-risk HPV genotypes are known as oncogenes because of their continuous expression, which leads to disruption of cell-cycle check points and cell genome instability through alteration of cellular p53 and retinoblastoma protein functions. This test is similar to LOINC 69358-0, which measures cells containing E6+E7 mRNA via flow cytometry.
status
ACTIVE
Fully-Specified Name
component
Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+66+68 E6+E7 mRNA
property
PrThr = Present or threshold: The Property PrThr stands for “Presence or Threshold”, meaning either a) the actual presence or absence of an analyte, or b) that the amount of analyte detected is over some predetermined threshold.
time
Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
Quick, Current, Complete - www.findacode.com