WT1 gene exon 1+2 transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method   72503-6

LOINC Code


LOINC code72503-6
nameWT1 gene exon 1+2 transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method
descriptionWilm's tumor (WT1) gene expression is calculated by measuring the copy numbers of transcripts within exon 1 and 2 of the WTI gene compared to transcripts from a control gene. The WT1 gene expression is used as a specific molecular marker to improve diagnosis, prognosis and follow-up of adult acute myeloid leukemia (AML) patients. Early decreased expression of WT1 copy number in peripheral blood predicts better outcome for AML patients [PMID:20107153]. This code is based on, but not limited in use to, the submitter's package insert, Ipsogen's ProfileQuant® kit. This kit uses real-time quantitative PCR to quantify WT1 gene expression relative to ABL1 control gene.
statusACTIVE

Fully-Specified Name

componentWT1 gene exon 1+2 transcript/control transcript
propertyNRto  =  Number Ratio
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemBld/Tiss
    Bld  =  Whole blood
    Tiss  =  Tissue, unspecified
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
methodMolgen  =  Molecular Genetics:  General class of methods used to detect genetic attributes on a molecular basis including RFL, PCR and other methods.

Additional Names

short nameWT1 ex 1+2/control Bld/T

Basic Attributes

classMOLPATH.MUT
type1  Laboratory
order vs. observationBoth
formula (readable)Normalized copy number (NCN) = [WT1 copy number/ABL1 copy number] x 10000
example UCUM units%
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unit%

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.42
last change typeMIN  - change to field other than name

Related Names

ABL
ABL1
ABL1 transcript
AWT1
Blood
control gene
EWS-WT1
Genetics
GUD
Heredity
Heritable
i
II
Inherited
Molecular genetics
Molecular pathology
MOLPATH
MOLPATH.MUTATIONS
NPHS4
Number ratio
PCR
Point in time
QNT
Quan
Quant
Quantitative
Random
Tissue
Tissue, unspecified
WAGR
WB
Whole blood
Whole blood or Tissue
Wilms tumor 1
WIT-2
WT1 ex 1+2
WT33

Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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