3-Hydroxy-3-Methylglutaryl-coenzyme A reductase Ab [Units/volume] in Serum by Line blot   82388-0

LOINC Code


LOINC code82388-0
name3-Hydroxy-3-Methylglutaryl-coenzyme A reductase Ab [Units/volume] in Serum by Line blot
descriptionThis term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
statusACTIVE

Fully-Specified Name

component3-Hydroxy-3-Methylglutaryl-coenzyme A reductase Ab
propertyACnc  =  Arbitrary Concentration
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer  =  Serum
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
methodLine blot  =  Line blot:  A membrane strip pre-coated with a specific set of antigens in parallel lines that are incubated with antibodies in order to detect the targets of interest.

Additional Names

short nameHMGCR Ab Ser Line blot-aCnc

Basic Attributes

classSERO
type1  Laboratory
order vs. observationBoth
example UCUM units[arb'U]/mL
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitarb U/mL

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.68
last change typeMIN  - change to field other than name
change reasonThis term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.

Related Names

3-OH-3-Methylglutaryl-coA reductase Ab
ABS
Aby
Antby
Anti
Antibodies
Antibody
Arbitrary concentration
Autoantibodies
Autoantibody
HMGCR
Hydrox
III
NAM
Necrotizing autoimmune myopathy
OH
Point in time
QNT
Quan
Quant
Quantitative
Random
Serology
Serum
SR

Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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