82937-4
LOINC Code
| LOINC code | 82937-4 | |
|---|---|---|
| name | ||
| description | Analysis of SLAM (signaling lymphocytic activation molecule)-associated protein (SAP) and X-linked inhibitor of apoptosis protein (XIAP) levels by flow cytometry is performed as a preliminary screen for X-linked lymphoproliferative (XLP) disease and X-linked familial hemophagocytic lymphohistiocytosis (HLH). If SAP protein levels are absent or decreased, XLP is suspected. If XIAP protein levels are absent or decreased, HLH (aka XLP-2) is suspected. The diagnosis is confirmed by genetic analysis of the associated genes (SH2D1A gene for XLP, BIRC4 gene for HLH). | |
| status | ACTIVE | |
Fully-Specified Name | ||
| component | Signaling lymphocytic activation molecule (SLAM)-associated & X-linked inhibitor of apoptosis protein | |
| property | Imp = Impression/interpretation of study | |
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | |
| system | WBC = Leukocytes | |
| scale | Nom = Nominal: Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody. | |
| method | Flow cytometry | |
Additional Names | ||
| short name | (SLAM)-associated protein; Assoc; BIRC4; Chemistry; Duncan disease; Dynamic; Esoteric; FC; Hemophagocytic Lymphohistiocytosis; HLH; Impression; Impression/interpretation of study; Impressions; Inhib; Inhibit; Interp; Interpretation; Leukocytes; Nominal; P | |
Basic Attributes | ||
| class | CHEM | |
| type | 1 Laboratory | |
| order vs. observation | SAP + XIAP WBC | |
History/Usage | ||
| first released | ||
| last updated | 2.58 | |
| last change type | ADD - added | |
Related Names | ||
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