85380-4

LOINC Code


LOINC code85380-4
name
descriptionThis term is used to report the interpretation of results from an HIV immunoassay testing algorithm that may be based on third, fourth, fifth and possibly other generations of HIV immunoassays. HIV testing has evolved significantly in the past 30 years. The first three generations of HIV immunoassays detected HIV antibodies (first IgG only, then IgG and IgM). The fourth-generation tests can detect, but not differentiate between, HIV-1 and HIV-2 antibodies as well as the HIV-1 p24 antigen. The inclusion of the p24 antigen allows for detection of HIV as early as two weeks after exposure and before seroconversion occurs (i.e. before antibodies are produced). In 2014, the U.S. Centers for Disease Control and Prevention published a recommended algorithm for HIV diagnostic testing based on fourth-generation HIV immunoassays [https://stacks.cdc.gov/view/cdc23447]. More recently, fifth-generation HIV immunoassays have been developed, which can detect and differentiate between HIV-1 and HIV-2 antibodies and the HIV-1 p24 antigen. The CDC is in the process of updating its testing algorithm and the latest information can be found at https://www.cdc.gov/hiv/testing/laboratorytests.html. Note that third generation assays are still available in the U.S. and earlier generations may also be available outside the U.S.
statusACTIVE

Fully-Specified Name

componentHIV immunoassay testing algorithm interpretation
propertyImp  =  Impression/interpretation of study
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer/Plas/Bld
    Ser  =  Serum
    Plas  =  Plasma
    Bld  =  Whole blood
scaleNom  =  Nominal:  Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody.
method

Additional Names

short nameAIDS; Blood; HIV IA algorithm interp; HIV imm testing algorithm; Human immunodeficiency virus; ID; Impression; Impression/interpretation of study; Impressions; Infectious Disease; InfectiousDisease; Interp; Interpret; Interpretation; Interpt; Intrp; Micro

Basic Attributes

classMICRO
type1  Laboratory
order vs. observationHIV IA algorith

History/Usage

first released
last updated2.61
last change typeADD  - added

Related Names



Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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