90735-2
LOINC Code
| LOINC code | 90735-2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| name | |||||||||
| description | The tests in this panel detect glycosylphosphatidylinositol (GPI)-linked proteins including CD14 for monocytes, CD16 and 24 for granulocytes, and CD59 for erythrocytes. In addition, fluorescent aerolysin (FLAER) which selectively binds to GPI anchor proteins, is also used to detect the presence or absence of those anchors. Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematologic disorder of erythroid, granulocytic, and megakaryocytic cell lines. The abnormal cells in PNH are missing the GPI-linked proteins due to mutations in the phosphatidylinositol glycan A gene (PIGA). | ||||||||
| status | ACTIVE | ||||||||
Fully-Specified Name | |||||||||
| component | Paroxysmal nocturnal hemoglobinuria GPI-Linked WBC & RBC Ag Panel | ||||||||
| property | - | ||||||||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||||||||
| system | Bld = Whole blood | ||||||||
| scale | - | ||||||||
| method | |||||||||
Additional Names | |||||||||
| short name | Blood; CELL MARKERS; Glycosylphosphatidylinositol-linked proteins; Pan; PANEL.CELLMARK; Panl; Paroxysmal nocturnal hemoglobinuria; PLINK; PNH; PNH GPI-Linked WBC + RBC; PNH GPI-Lkd WBC + RBC Ag; PNH GPI-Lkd WBC + RBC Ag Pnl; Pnl; Point in time; Random; WB | ||||||||
Basic Attributes | |||||||||
| class | PANEL.CELLMARK | ||||||||
| type | 1 Laboratory | ||||||||
| order vs. observation | PNH GPI-Lkd WBC | ||||||||
Panel Components | |||||||||
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History/Usage | |||||||||
| first released | |||||||||
| last updated | 2.65 | ||||||||
| last change type | ADD - added | ||||||||
Related Names | |||||||||
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