Warfarin response genotype panel - Blood or Tissue by Molecular genetics method 93196-4
LOINC Code
| LOINC code | 93196-4 | ||
|---|---|---|---|
| name | Warfarin response genotype panel - Blood or Tissue by Molecular genetics method | ||
| description | This panel contains genotype results for warfarin dosing. As of 2019, CYP2C9, VKORC1, CYP4F2, and rs12777823 genotypes are used when available to help determine a patient's initial therapeutic warfarin dose. VKORC1 and CYP2C9 genotypes are the most important genetic determinants of warfarin dosing. Additionally, a genetic variation in the CYP4F2 gene, CYP4F2*3, as well as a variant near the CYP2C gene cluster, rs12777823, have been associated with influencing warfarin therapy.[NCBI Books: NBK84174] This panel is based on, but not limited in use to, the 2017 Update of the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing, which provides warfarin dosing recommendations for adults with and without African ancestry, and also for pediatric patients.[https://cpicpgx.org/content/guideline/publication/warfarin/2017/warfarin.pdf] | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | Warfarin response genotype panel | ||
| property | - | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | Bld/Tiss Bld = Whole blood Tiss = Tissue, unspecified | ||
| scale | - | ||
| method | Molgen = Molecular Genetics: General class of methods used to detect genetic attributes on a molecular basis including RFL, PCR and other methods. | ||
Additional Names | |||
| short name | Warfarin genotype pnl Bld/T | ||
Basic Attributes | |||
| class | PANEL.MOLPATH.PHARMG | ||
| type | 1 Laboratory | ||
| order vs. observation | Order | ||
Panel Components | |||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
History/Usage | |||
| first released | |||
| last updated | 2.67 | ||
| last change type | ADD - added | ||
Related Names | |||
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