94718-4

LOINC Code


LOINC code94718-4
name
descriptionQualitative detection of human neutrophil peptide-1, -2, and -3, also known as alpha defensins 1-3, in synovial fluid by immunoassay methods, such as ELISA or lateral flow assay, for the diagnosis of periprosthetic joint infections (PJI). This assay detects but does not differentiate between the three HNP peptides. This term was created for, but not limited in use to, Zimmer Biomet Diagnostics Synovasure Alpha Defensin ELISA and Lateral Flow Test kits. The Synovasure Lateral flow test utilizes the same anti-microbial peptide as the ELISA test to detect the immune response to infection, but the Lateral Flow returns results in 10 minute whereas the ELISA typically has a 24-48 hour result turnaround.
statusACTIVE

Fully-Specified Name

componentAlpha defensins 1+2+3
propertyPrThr  =  Present or threshold:  The Property PrThr stands for “Presence or Threshold”, meaning either a) the actual presence or absence of an analyte, or b) that the amount of analyte detected is over some predetermined threshold.
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSynv fld  =  Synovial fluid (Joint fluid)
scaleOrd  =  Ordinal:  Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive.
methodIA  =  Immunoassay:  Encompasses all immunoassays with a few exceptions, including Immune Blot and Immune Fluorescence, which were created based on historic usage.

Additional Names

short nameAlfa; Alpha defensin; alpha Defensins; Chemistry; EIA; ELFA; ELISA; Enzyme immunoassay; HNP-1; HNP-2; HNP-3; Human neutrophil peptide; Human neutrophil peptides; i; IAA; ID; II; III; Infectious Disease; InfectiousDisease; Joint aspirate; Joint fld; Joint

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationAlpha defensins

History/Usage

first released
last updated2.72
last change typeMIN  - change to field other than name

Related Names



Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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