14117-6

LOINC Code


LOINC code14117-6
name
descriptionRatio of a patient's IgG and albumin in CSF to the IgG and albumin in serum is of diagnostic value in a number of neurological disorders. Normally CSF albumin and IgG are derived from the serum, whereas in patients with active multiple sclerosis, the increased CSF IgG is believed to be synthesized within the CSF. The CSF Index is a calculated value which expresses the ratio of IgG to albumin in CSF, to the ratio of IgG to albumin in serum. An elevated ratio suggests local CNS synthesis of IgG. An increased CSF/IgG Index is found in diseases such as MS, neurosyphilis, subacute sclerosing panencephalitis (SSPE), chronic CNS infections and CNS lupus erythematosus.
statusACTIVE

Fully-Specified Name

componentIgG clearance/Albumin clearance
propertyRatio
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer+CSF
    Ser  =  Serum
    CSF  =  Cerebral spinal fluid
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short nameAlb; Alb clear; Both serum and cerebrospinal fluid; Cerebral spinal fluid; Cerebrospinal Fl; Chemistry; Cl; Clear; Clearanc; Clearances; Clr; Immune globulin G; Immunoglobulin G; Point in time; Protein.albumin; QNT; Quan; Quant; Quantitative; Random; Rati

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationIgG/Alb clear S
formula (readable)IgG index = (IgG, CSF/IgG, serum)/(albumin, CSF/albumin,serum)

Member of these Panels

55121-8

History/Usage

first released
last updated2.73
last change typeMIN  - change to field other than name

Related Names

Y

Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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