53709-2

LOINC Code


LOINC code53709-2
name
descriptionGlial Nuclear Antibody (AGNA) Type 1 antibody is a marker found in paraneoplastic syndrome associated with small cell lung carcinoma (SCLC). It is also closely associated with paraneoplastic Lambert-Eaton Myasthenia Syndrome (LEMS). There appears to be a tight association between AGNA and voltage-gated calcium channel antibodies in patients with SCLC. Patients with AGNA have characteristic nuclear staining of the Bergmann glia in the Purkinje cell layer of the cerebellum. Information from "Paraneoplastic limbic encephalitis associated with potassium channel antibodies: value of anti-glial nuclear antibodies in identifying the tumour" by L. Zuliani, A. Saiz, B. Tavolato, B. Giometto, A. Vincent and Francesc Graus, JNNPm 2007; 78; p. 204-205.
statusACTIVE

Fully-Specified Name

componentGlial nuclear type 1 Ab
propertyTitr  =  Dilution Factor (Titer)
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer  =  Serum
scaleSemiQn
method

Additional Names

short nameABS; Aby; AGNA; AGNA-1; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Dilution factor; Dilution Factor (Titer); Glial nuc type 1; i; Lambert-Eaton myasthenic syndrome; Nuc; Paraneoplastic Antibody; Paraneoplastic syndrome; Point in time

Basic Attributes

classSERO
type1  Laboratory
order vs. observationGlial nuc type
example UCUM unitstiter
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)

Member of these Panels

43104-9

History/Usage

first released
last updated2.75
last change typeMAJ  - change to name field other than Component;
change reason{titer}

Related Names

N

Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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