Participants are asked to fast for at least 9 hours (generally overnight) prior to the Fasting Plasma Glucose test. Participants are asked a series of exclusionary questions and then have blood drawn. The plasma is separated from the blood via centrifugation and glucose concentration is determined via a hexokinase-mediated reaction. If the 9-hour fast is not met, the Diabetes Working Group recommends that the test can still be completed as a "casual" glucose concentration (see the protocol for casual glucose reference ranges for screening plus/minus Diabetes). The Diabetes Working Group refers users to the Fasting Plasma Proinsulin assay in Diabetes Supplemental Information to obtain more information about insulin resistance.
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