75406-9

LOINC Code


LOINC code75406-9
name
descriptionDetects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16, 18, and 45 in cervical specimens from women with positive HPV assay results. For women 21-years and older with atypical squamous cells of undetermined significance (ASC-US) cervical cytology results, and HPV positive assay results, this assay can be used to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45. For women 30-years and older, the HPV 16, 18, and/or 45 genotype assay can be used to test samples from women with HPV assay positive results, along with cervical cytology results. This assay has not been evaluated for HPV vaccinated patients or in cases of suspected abuse. It differentiates HPV 16 from HPV 18 and/or HPV 45, but does not differentiate HPV 18 and HPV 45. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay which uses target capture, target amplification by transcription-mediated amplification and detection of the amplification products by hybridization protection.
statusDEPRECATED
Replacements

alternatives to this code:

82354-2

Fully-Specified Name

componentHuman papilloma virus 16 & 18+45 E6+E7 mRNA
propertyPrThr  =  Present or threshold:  The Property PrThr stands for “Presence or Threshold”, meaning either a) the actual presence or absence of an analyte, or b) that the amount of analyte detected is over some predetermined threshold.
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemCvx  =  Cervix
scaleOrd  =  Ordinal:  Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive.
methodProbe.amp

Additional Names

short nameAmplif; Amplification; Amplified; Cervix; DNA NUCLEIC ACID PROBE; DNA probe; Genital tract; Genital warts; Gyn; Gynecology; HPV; HPV 16 & 18+45; HPV16; HPV16 and 18; HPV16+18; HPV16+18+45 E6+E7mRNA; Human papillomavirus; ID; Infectious Disease; Infectious

Basic Attributes

classMICRO
type1  Laboratory
order vs. observationDeprecated HPV1

Member of these Panels

82963-0
82963-0
79542-7

History/Usage

first released
last updated2.58
last change typeDEL  - delete (deprecate)

Related Names



Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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