76479-5

LOINC Code


LOINC code76479-5
name
descriptionAn interpretation of the acetylcholinesterase (AChE) in amniotic fluid testing result which is used as an aid to diagnose open neural tube defect (NDT) and ventral wall defects. The two most common neural tube defects are spina bifida and anencephaly. When an NTD is suspected based upon maternal serum alpha-fetoprotein (AFP) screening results, or diagnosed via ultrasound, detection of acetylcholinesterase (AChE) in amniotic fluid is a useful diagnostic tool as normal amniotic fluid does not contain AChE, unless from the fetus as a result of an open NTD. The patient's gestational age must be at least 13 weeks (second trimester) for accurate AChE detection. Optimal gestational age is 14 to 18 weeks. If acetylcholinesterase is present genetic consultation and high-resolution ultrasound may be suggested.
statusACTIVE

Fully-Specified Name

componentAcetylcholinesterase
propertyImp  =  Impression/interpretation of study
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemAmnio fld  =  Amniotic fluid
scaleNar  =  Narrative:  Text narrative, such as the description of a microscopic part of a surgical papule test.
method

Additional Names

short nameAcetycholinesterase; Acetylcholine acetylhydrolase; Acetylhydrolase; AChE; ACLE; AF; Amn; Amn fl; Amnio; Amniotic flu; Amniotic fluid; Chemistry; Choline esterase I; Cholinesterase true; Erythrocyte cholinesterase; Impression; Impression/interpretation of

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationAChE Amn-Imp

Member of these Panels

76478-7

History/Usage

first released
last updated2.73
last change typeMIN  - change to field other than name

Related Names



Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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