76546-1
LOINC Code
| LOINC code | 76546-1 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| name | |||||||||
| description | A 10-year breast cancer distant recurrence risk panel created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone. The panel includes terms for primary tumor size, lymph node status, distant recurrence risk score, and distance recurrence risk classification. The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years. | ||||||||
| status | ACTIVE | ||||||||
Fully-Specified Name | |||||||||
| component | Breast cancer 10Y risk of distant recurrence panel | ||||||||
| property | - | ||||||||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||||||||
| system | ^Patient | ||||||||
| scale | - | ||||||||
| method | Prosigna | ||||||||
Additional Names | |||||||||
| short name | breast cancer; Brst ca10Y risk dist recur Pnl; Molecular pathology; MOLPATH; PAM50; Pan; Panel.molpath; Panl; Pnl; Point in time; Prosigna; Psoriasis Care Satisfaction questionnaire; Random | ||||||||
Basic Attributes | |||||||||
| class | PANEL.MOLPATH | ||||||||
| type | 1 Laboratory | ||||||||
| order vs. observation | Brst ca 10Y ris | ||||||||
Panel Components | |||||||||
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History/Usage | |||||||||
| first released | |||||||||
| last updated | 2.52 | ||||||||
| last change type | MIN - change to field other than name | ||||||||
Related Names | |||||||||
Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
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