Heart transplant acute cellular rejection risk [Score] in Mononuclear cells Calculated by AlloMap 79102-0
LOINC Code
| LOINC code | 79102-0 | ||
|---|---|---|---|
| name | Heart transplant acute cellular rejection risk [Score] in Mononuclear cells Calculated by AlloMap | ||
| description | This term is used to report the risk score for moderate to severe (grade 3A or higher) acute cellular transplant rejection in heart transplant recipients with stable allograft function. The test assesses the expression of 11 genes (ITGAM, FLT3, IL1R2, G6B, PF4, WDR40A, MIR, ARHU, PDCD1, ITGA4 AND SEMA7A) using PCR with RNA isolated from peripheral blood mononuclear cells, and the gene expression data is then used to calculate a score that ranges from 0-40, with a lower score indicating a lower risk for rejection. In the Cardiac Allograft Rejection Gene Expression Observational (CARGO) study, patients who were at least 12 months post-transplant and who had a score less than 30 were very unlikely to have grade 3A acute cellular rejection at the time of testing (negative predictive value 99.6%). [PMID: 16433769] This term was created for XDx Reference Laboratory's AlloMap test, which is indicated for heart transplant patients who are at least 15 years of age and 55 or more days post-transplant. | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | Heart transplant acute cellular rejection risk | ||
| property | Score | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | Bld MC Bld = Whole blood | ||
| scale | Qn = Quantitative: The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256 | ||
| method | Calculated.AlloMap | ||
Additional Names | |||
| short name | Heart tx acute reject Score MC AlloMap | ||
Basic Attributes | |||
| class | MOLPATH | ||
| type | 1 Laboratory | ||
| order vs. observation | Both | ||
| example UCUM units | {score} The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org) | ||
| example unit | score | ||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
History/Usage | |||
| test rank | 8516 of 2000 most commonly performed tests by labs in USA | ||
| first released | |||
| last updated | 2.73 | ||
| last change type | MIN - change to field other than name | ||
Related Names | |||
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Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
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