Folate and tryptophan and metabolites panel - Cerebral spinal fluid   79572-4

LOINC Code


LOINC code79572-4
nameFolate and tryptophan and metabolites panel - Cerebral spinal fluid
descriptionTesting for folate and its metabolites as well as tryptophan and its metabolites in CSF can be useful in distinguishing among various central nervous system disorders associated with folate deficiency. Low folate levels are associated with inborn errors of metabolism, including cerebral folate deficiency (CFD), a neurological syndrome that occurs around 2-4 months of age and is primarily associated with associated with low levels of 5-methyltetrahydrofolate (5-MTHF) in the CSF with normal folate levels in the plasma and red blood cells.[PMID: 19260931] Low folate levels are also associated with depression and dementia in elderly patients.[PMID: 11183038] Serotonin, which is formed from tryptophan, may be the link between folate and depression or dementia. Many patients with neuropsychiatric disorders and folate deficiency have also been found to have low levels of 5-hydroxyindoleacetic acid (5-HIAA, a serotonin metabolite), and patients with 5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency also have decreased serotonin synthesis. [PMCID: 1810582]
statusACTIVE

Fully-Specified Name

componentFolate & tryptophan & metabolites panel
property-
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemCSF  =  Cerebral spinal fluid
scale-
method

Additional Names

short nameFolate + Tryp + Metabs Pnl CSF

Basic Attributes

classPANEL.CHEM
type1  Laboratory
order vs. observationOrder

Panel Components

47547-55-Methyltetrahydrofolate [Moles/volume] in Cerebral spinal fluid
75048-9Tetrahydrofolate [Moles/volume] in Cerebral spinal fluid
26602-3Tryptophan [Moles/volume] in Cerebral spinal fluid
47544-25-Hydroxyindoleacetate [Moles/volume] in Cerebral spinal fluid
47546-75-Hydroxytryptophan [Moles/volume] in Cerebral spinal fluid
79574-0Folate and tryptophan and metabolites pattern [Interpretation] in Cerebral spinal fluid Narrative

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.54
last change typeMIN  - change to field other than name

Related Names

c244
Cerebral spinal fluid
Cerebrospinal Fl
Chemistry
Folat
Folate + Tryp + Metabs Pnl
Folic acid
L-tryptophan
Metabolite
Metb
Pan
PANEL.CHEMISTRY
Panl
Pnl
Point in time
Pteroylglutamate
Pteroylglutamic acid
Random
Spinal Fl
Spinal Fld
Spinal Flu
Spinal Fluid
Trp
Vit M
Vitamin M

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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