83056-2
LOINC Code
| LOINC code | 83056-2 | |
|---|---|---|
| name | ||
| description | This term should be used to report the narrative impression of PD-L1 (CD274) protein expression in tumor cells as determined by immune staining with anti-PD-L1 clone 28-8. Patients with certain cancers, such as non-squamous non small cell lung cancer (NSCLC) or melanoma, whose tumors are positive for PD-L1 by 28-8 may be eligible for anti-programmed death 1 (PD-1) receptor antibody therapy, which effectively prevents the binding of PD-L1 to PD-1. The percentage of viable tumor cells that show partial or complete PD-L1 membrane staining is reported using [LOINC: 83053-9], and the ordinal staining result using [LOINC: 83055-4]. This term was created for, but is not limited in use to, the Dako PD-L1 28-8 pharmDx test kit, which, as of November 2016, is FDA-approved as a companion diagnostic to assess whether patients with certain cancers are eligible for nivolumab therapy. | |
| status | ACTIVE | |
Fully-Specified Name | ||
| component | Programmed cell death ligand 1 by clone 28-8 | |
| property | Imp = Impression/interpretation of study | |
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | |
| system | Tiss = Tissue, unspecified | |
| scale | Nar = Narrative: Text narrative, such as the description of a microscopic part of a surgical papule test. | |
| method | Immune stain | |
Additional Names | ||
| short name | B7 homolog 1; B7-H1; CD274; Cluster of differentiation 274; i; IHC; Imm; Immunohistochemical stain; Immunostain; Impression; Impression/interpretation of study; Impressions; ImStn; Imun; Imune; Interp; Interpretation; Narrative; Pathology; PDL1; PD-L1; PD | |
Basic Attributes | ||
| class | PATH | |
| type | 1 Laboratory | |
| order vs. observation | PD-L1 by 28-8 T | |
History/Usage | ||
| first released | ||
| last updated | 2.58 | |
| last change type | ADD - added | |
Related Names | ||
Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
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