Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot 85092-5
LOINC Code
| LOINC code | 85092-5 | ||
|---|---|---|---|
| name | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot | ||
| description | This panel contains results for the presence of IgG autoantibodies in serum or plasma for the diagnosis of autoimmune liver diseases, including autoimmune hepatitis and primary biliary cirrhosis. This panel was created for, but not limited in use to, the submitter's test strip, a membrane strip pre-coated with the following antigens: AMA-M2, M2-3E, Sp100, PML, gp210, LKM-1, LC-1, SLA/LP, SS-A, Ro-52, Scl-70, CENP A, CENP B and PGDH. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot. | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | Liver diseases autoimmune Ab.IgG panel | ||
| property | - | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | Ser/Plas Ser = Serum Plas = Plasma | ||
| scale | - | ||
| method | Line blot = Line blot: A membrane strip pre-coated with a specific set of antigens in parallel lines that are incubated with antibodies in order to detect the targets of interest. | ||
Additional Names | |||
| short name | Liver diseases IgG Pnl SerPl Line blot | ||
Basic Attributes | |||
| class | PANEL.SERO | ||
| type | 1 Laboratory | ||
| order vs. observation | Order | ||
Panel Components | |||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
History/Usage | |||
| first released | |||
| last updated | 2.68 | ||
| last change type | NAM - change to Analyte/Component | ||
| change reason | Release 2.68: COMPONENT: Updated for naming consistency across autoimmune panels.; Previous Releases: This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description. | ||
Related Names | |||
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Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
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