88460-1

LOINC Code


LOINC code88460-1
name
descriptionThe SRA test is a functional assay that measures heparin-dependent platelet activation. Patient serum is incubated with donor platelets containing radioactive 14C serotonin and different concentrations of heparin. Antibody present in the patient serum will bind and activate donor platelets, releasing radiolabeled serotonin from the platelet granules. A positive SRA is expected to show >20% release of the 14C serotonin when mixed with patient serum and low-dose heparin. In addition, the high-dose heparin must reduce the % release obtained with low-dose heparin by at least 50% in order to demonstrate that the platelet activation is heparin dependent.
statusACTIVE

Fully-Specified Name

componentSerotonin release 50 IU/mL heparin.low molecular weight
    IU  =  Intrauterine
propertyACnc  =  Arbitrary Concentration
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer  =  Serum
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short name5-HT; 5-hydroxytryptamine; 5-hydroxytryptophane; Arbitrary concentration; C10H12N2O; Clexane; Enoxaparin; Enteramine; Hep; Hepar; Heparin dependent platelet antibody; Heparn; HIT/HITT; LMWH; LMWH-induced thrombocytopenia; Lovenox; Point in time; QNT; Quan

Basic Attributes

classSERO
type1  Laboratory
order vs. observationSRA 50 IU/mL LM
example UCUM units%
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)

History/Usage

first released
last updated2.64
last change typeADD  - added
change reason%

Related Names



Copyright © 2026 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2026, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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