SARS-CoV-2 (COVID-19) S protein RBD neutralizing antibody [Presence] in Serum or Plasma by sVNT   96603-6

LOINC Code


LOINC code96603-6
nameSARS-CoV-2 (COVID-19) S protein RBD neutralizing antibody [Presence] in Serum or Plasma by sVNT
descriptionQualitative results for detection of neutralizing antibodies (NAbs) that block the binding of the S (spike) protein receptor binding domain (RDB) from SARS Coronavirus 2 (SARS-CoV-2) to ACE2 receptor protein in serum or plasma specimens by surrogate virus neutralization testing (sVNT), which is an immunoassay-based method. Neutralizing antibody testing is performed to determine whether the antibodies produced after SARS-CoV-2 infection or in response to a vaccination are able to neutralize the virus and prevent infection or re-infection. Different methods can be used to determine the presence of neutralizing antibodies, including conventional VNT (virus neutralization test, cVNT), pseudovirus VNT (pVNT), and surrogate VNT (sVNT). The sVNT method currently employs purified proteins in an immunoassay-based format, takes less time to complete, and does not require the use of live virus compared to cVNT and pVNT methods.
statusACTIVE

Fully-Specified Name

componentSARS coronavirus 2 spike protein RBD Ab.neut
propertyPrThr  =  Present or threshold:  The Property PrThr stands for “Presence or Threshold”, meaning either a) the actual presence or absence of an analyte, or b) that the amount of analyte detected is over some predetermined threshold.
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer/Plas
    Ser  =  Serum
    Plas  =  Plasma
scaleOrd  =  Ordinal:  Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive.
methodsVNT

Additional Names

short nameSARS-CoV-2 S RBD NAb SerPl Ql sVNT

Basic Attributes

classMICRO
type1  Laboratory
order vs. observationBoth

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.72
last change typeMAJ  - change to name field other than Component;
change reasonRelease 2.72: METHOD_TYP: Updated to further specify the type of neutralization assay method used.;

Related Names

2019 Novel Coronavirus
2019-nCoV
ABS
Aby
Antby
Anti
Antibodies
Antibody
Autoantibodies
Autoantibody
Corona virus
COVID19
COVID-19
ID
II
Infectious Disease
InfectiousDisease
Microbiology
NAb
Ordinal
Pl
Plasma
Plsm
Point in time
PR
Prot
QL
Qual
Qualitative
Random
SARS Coronavirus 1
SARS-CoV
SARS-CoV-1
SARS-CoV-2
SARS-CoV-2 S
SARS-CoV-2 S RBD
SARS-CoV-2 S RBD Nab
Screen
SerP
SerPl
SerPlas
Serum
Serum or plasma
Severe Acute Respiratory Syndrome
SR
surrogate virus neutralization testing
sVNT
Viral Pneumonias
Wuhan coronavirus

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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