New CPT Proprietary Lab Analysis (PLA) codes

The following PLA codes are effective January 1, 2020: New PLA codes: CPT Code Long Descriptor Effective Date 0139U Neurology (autism spectrum disorder [ASD]), quantitative measurements of 6 central carbon metabolites (ie, a-ketoglutarate, alanine, lactate, phenylalanine, pyruvate, and succinate), LC-MS/MS, plasma, algorithmic analysis with result reported as negative or positive (with metabolic subtypes of ASD) January 1, 2020 0140U Infectious disease (fungi), fungal pathogen identification, DNA (15 fungal targets), blood culture, amplified probe technique, each target reported as detected or not detected January 1, 2020 0141U Infectious disease (bacteria and fungi), gram-positive organism identification and drug resistance element detection...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This premium coding update covers new CPT Proprietary Laboratory Analysis (PLA) codes effective January 1, 2020. It is relevant to laboratory coders, billing teams, compliance staff, and clinicians who work with molecular diagnostics, infectious disease testing, oncology, drug assay reporting, and hereditary cancer testing. The article presents the new PLA additions in a structured format so readers can review the scope of the code changes and identify the laboratory service categories affected.

Why This Topic Matters

PLA code updates can affect laboratory claim reporting, charge capture, and coding workflows for molecular and other specialized tests. Reviewing these additions helps organizations recognize which test categories were updated and monitor changes tied to annual CPT code maintenance.

What You Will Learn

  • Which laboratory medicine areas were represented in the new PLA code additions
  • How the 2020 effective-date update is organized
  • Which general categories of testing and analysis are included in the list
  • How to identify whether a test area may be affected by the PLA update

Who Should Read This

  • Medical coders
  • Laboratory billing staff
  • Compliance professionals
  • Pathology and laboratory medicine staff
  • Revenue cycle teams

Codes Discussed

  • CPT: 0139U
  • CPT: 0140U
  • CPT: 0141U
  • CPT: 0142U
  • CPT: 0143U
  • CPT: 0144U
  • CPT: 0145U
  • CPT: 0146U
  • CPT: 0147U
  • CPT: 0148U
  • CPT: 0149U
  • CPT: 0150U
  • CPT: 0151U
  • CPT: 0152U
  • CPT: 0153U
  • CPT: 0154U
  • CPT: 0155U
  • CPT: 0156U
  • CPT: 0157U
  • CPT: 0158U
  • CPT: 0159U
  • CPT: 0160U
  • CPT: 0161U
  • CPT: 0162U

Modifiers Discussed

  • CPT: +

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