AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2025 Issue 4; New/Revised ICD-10-CM Codes

Abnormal Rheumatoid Factor or Anti-citrullinated Protein Antibody with and without Rheumatoid Arthritis

Codes M05.A, Abnormal rheumatoid factor and anti-citrullinated protein antibody with rheumatoid arthritis, and R76.81, Abnormal rheumatoid factor and anti-citrullinated protein antibody without rheumatoid arthritis, were created to capture abnormal rheumatoid factor and abnormal anti-citrullinated protein antibodies in individuals with and without rheumatoid arthritis. Abnormal RA-related immunologic tests measure rheumatoid factor (RF) and/or anti-citrullinated protein antibody (ACPA). These abnormal test findings can be predictive of the future onset of clinical rheumatoid arthritis.High levels of rheumatoid factor in the blood are typically caused by autoimmune diseases, such as rheumatoid arthritis, Sjogren’s syndrome and systemic lupus erythematosus...

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