AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2019 Issue 4; New/Revised ICD-10-CM Codes
Adenosine Deaminase Deficiency
Code D81.31, Severe combined immunodeficiency due to adenosine deaminase deficiency, was created for adenosine deaminase (ADA) deficiency that damages the immune system and causes severe combined immunodeficiency (SCID), which is commonly referred to as SCID due to ADA deficiency. ADA is an inherited disorder of purine metabolism that is characterized by the accumulation of deoxyadenosine, a molecule that is toxic to lymphocytes, the cells that make up the immune system. The loss of infection-fighting lymphocytes results in the signs and symptoms of SCID. SCID due to ADA deficiency may present before 6 months of age. The individual experiences...
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Article Overview
This article covers adenosine deaminase deficiency and related conditions in ICD-10-CM, with background on the clinical features, diagnostic context, and broad treatment approaches discussed in the source. It is relevant to coders, CDI professionals, billers, and clinicians who work with immunology, genetics, and rare disease documentation.
Why This Topic Matters
The article helps readers understand how this rare-disease topic is organized in ICD-10-CM and why documentation details matter when distinguishing among closely related deficiency states.
What You Will Learn
- How the article frames adenosine deaminase deficiency within ICD-10-CM
- The broad clinical distinctions discussed between related deficiency conditions
- The general diagnostic and treatment context described for these rare disorders
- Which coding update topic areas are associated with ADA and ADA2 deficiency
Who Should Read This
- Medical coders
- Coding auditors
- Clinical documentation integrity specialists
- Billers
- Clinicians
- Genetics and immunology staff
Codes Discussed
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