
AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2025 Issue 2; Ask the Editor
Factor V Leiden
A patient with a diagnosis of factor V Leiden presented to the office for a follow-up encounter and the provider documented that the patient’s Coumadin was adjusted. When referencing “mutation, factor V Leiden” in the Alphabetic Index, the coding professional arrives at code D68.51, Activated protein C resistance. When referencing “deficiency, factor, V” the coding professional arrives at code D68.2, Hereditary deficiency of other clotting factors. There is no default code for “Factor V Leiden” without referencing the terms “mutation” or “deficiency.” What is the appropriate code assignment when only factor V Leiden is documented by the provider? ...
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