Intrahepatic Cholestasis of Pregnancy

A new subcategory O26.64, Intrahepatic cholestasis of pregnancy, has been created with codes to describe pregnancy related intrahepatic cholestasis (ICP) as follows:• O26.641, Intrahepatic cholestasis of pregnancy, first trimester • O26.642, Intrahepatic cholestasis of pregnancy, second trimester • O26.643, Intrahepatic cholestasis of pregnancy, third trimester • O26.649, Intrahepatic cholestasis of pregnancy, unspecified trimester ICP, also referred to as cholestasis of pregnancy, is a pregnancy-specific liver disorder, in which bile acid transport in the liver is altered. This leads to a build-up of bile acid in the maternal circulation and the fetal amniotic fluid. The...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article explains a newly created ICD-10-CM subcategory for intrahepatic cholestasis of pregnancy and provides general background on the condition, including how it is described in pregnancy care and why it is clinically important. It is relevant to coding professionals, obstetric clinicians, and medical reviewers who need to understand the scope of the diagnosis category and its trimester-based structure.

Why This Topic Matters

Accurate identification of this diagnosis category supports clearer documentation and coding for a pregnancy-specific liver disorder with maternal and fetal implications. The article also helps readers recognize the broader clinical context associated with the condition.

What You Will Learn

  • What intrahepatic cholestasis of pregnancy is in a general clinical sense
  • That the article presents a pregnancy-related ICD-10-CM subcategory with trimester-based distinctions
  • Why the condition matters in obstetric care
  • What general maternal and fetal risks are associated with the condition
  • How the article frames the condition’s likely causes and typical resolution pattern

Who Should Read This

  • Medical coders
  • Coding auditors
  • Obstetric clinicians
  • Maternal-fetal medicine staff
  • Clinical documentation specialists

Codes Discussed

  • ICD-10-CM: O26.641
  • ICD-10-CM: O26.642
  • ICD-10-CM: O26.643
  • ICD-10-CM: O26.649

Code Ranges Discussed

  • ICD-10-CM: O26.64

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