Thalassemia

Effective October 1, 2011, new codes have been created to describe unspecified thalassemia (282.40), alpha thalassemia (282.43), beta thalassemia (282.44), delta-beta thalassemia (282.45), thalassemia minor (282.46), and hemoglobin E-beta thalassemia (282.47). Previously, there was no accurate estimate of the number of symptomatic non-sickle cell related thalassemia patients in the United States, since ICD 9 CM only provided code 282.49, Other thalassemia, to capture the wide spectrum of this condition. The new ICD 9 CM codes will assist in tracking and studying these patients. Thalassemia is a family of inherited hemoglobinopathies in which...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article explains thalassemia as a hereditary hemoglobin disorder and outlines ICD-9-CM updates effective October 1, 2011. It is useful for coders, billers, clinicians, and data analysts who need to understand how thalassemia-related diagnoses were reorganized for reporting, tracking, and study. The article also places thalassemia within the broader context of related hemolytic anemia and hemoglobinopathy code categories.

Why This Topic Matters

Accurate classification of thalassemia and related hemoglobin disorders affects diagnosis reporting, clinical data tracking, and population-level analysis. The article highlights how revised ICD-9-CM categories improved specificity for these conditions.

Article Sections

  1. Clinical overview of thalassemia

    Introduces thalassemia as an inherited hemoglobin disorder and summarizes its broad clinical spectrum, inheritance patterns, and major forms. It also discusses general manifestations and treatment approaches at a high level.

  2. ICD-9-CM thalassemia code updates effective October 1, 2011

    Describes the ICD-9-CM revisions for thalassemia and related categories, including the expanded structure for more specific classification. The section also notes broader changes in adjacent hemoglobinopathy and hereditary hemolytic anemia groupings.

  3. Related hemoglobinopathy and sickle-cell category revisions

    Summarizes changes affecting nearby ICD-9-CM diagnosis categories that intersect with thalassemia reporting. This includes updates to related sickle-cell and other hemoglobinopathy classifications.

What You Will Learn

  • How thalassemia is broadly characterized as a hereditary hemoglobin disorder
  • Why ICD-9-CM coding changes were introduced for thalassemia
  • What kinds of related hemoglobinopathy categories were revised alongside thalassemia
  • How the article frames the clinical spectrum and treatment context of thalassemia

Who Should Read This

  • Medical coders
  • Coding auditors
  • Revenue cycle professionals
  • Clinicians
  • Health information management professionals
  • Clinical data analysts

Codes Discussed

  • ICD-9-CM: 282.40
  • ICD-9-CM: 282.43
  • ICD-9-CM: 282.44
  • ICD-9-CM: 282.45
  • ICD-9-CM: 282.46
  • ICD-9-CM: 282.47
  • ICD-9-CM: 282.49
  • ICD-9-CM: 282.41
  • ICD-9-CM: 282.42
  • ICD-9-CM: 282.5
  • ICD-9-CM: 282.7
  • ICD-9-CM: 282
  • ICD-9-CM: 282.4

Code Ranges Discussed

  • ICD-9-CM: 282.60-282.69

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