Tumor Lysis Syndrome

Effective October 1, 2009, subcategory 277.8, Other specified disorders of metabolism, has been expanded to uniquely describe tumor lysis syndrome. This new code (277.88) captures both tumor lysis syndrome following cancer therapy and spontaneous tumor lysis syndrome. Previously, the tumor lysis syndrome was not specifically indexed in ICD-9-CM. Tumor lysis syndrome (TLS) refers to a group of serious, potentially life-threatening metabolic disturbances that can occur after antineoplastic therapy.TLS usually occurs following the administration of anti-cancer drugs; however, it can also develop spontaneously or as a result of radiation or corticosteroid therapy. It is often associated with...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This coding article reviews tumor lysis syndrome as a clinically significant metabolic complication associated with cancer treatment and, more rarely, spontaneous onset. It is written for coding professionals who need to understand the ICD-9-CM update, the clinical context of the condition, and the general documentation considerations discussed in the article.

Why This Topic Matters

Accurate identification of tumor lysis syndrome affects diagnosis coding, especially when the condition occurs in the setting of antineoplastic therapy or as a spontaneous event. The article also addresses related coding context for the cause of the condition in drug-induced cases and the way the topic was added to ICD-9-CM.

What You Will Learn

  • How tumor lysis syndrome is characterized in a coding and clinical context
  • Why the ICD-9-CM update for this condition matters
  • What types of circumstances are associated with the syndrome
  • What general coding considerations are mentioned for cases involving treatment-related causes

Who Should Read This

  • Medical coders
  • Coding auditors
  • Clinical documentation staff
  • Revenue cycle professionals

Codes Discussed

  • ICD-9-CM: 277.8
  • ICD-9-CM: 277.88
  • ICD-9-CM: V58.11
  • ICD-9-CM: 205.00

Code Ranges Discussed

  • ICD-9-CM: 277.8

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