AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2025 Issue 4; New/Revised ICD-10-CM Codes

Xylazine Toxicity

Subcategory T65.84, Toxic effect of xylazine, has been created, with new codes to identify xylazine toxicity. T65.841- Toxic effect of xylazine, accidental (unintentional) T65.842- Toxic effect of xylazine, intentional self-harm T65.843- Toxic effect of xylazine, assault T65.844- Toxic effect of xylazine, undetermined  The appropriate seventh character should be added to capture the episode of care. Xylazine is a non-opioid animal tranquilizer/anesthetic approved by the US Food and Drug Administration (FDA) for use in veterinary medicine. It is not approved for human use due to serious adverse effects including suppression of the respiratory...

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