Coding Brief: New Codes for Administration of RSV Immunoglobulin (November 2023)

November 2023 page 15 Coding Brief: New Codes for Administration of RSV Immunoglobulin During the September 2023 CPT Editorial Panel meeting, two new codes (96380, 96381) were established within the Therapeutic, Prophylactic, and Diagnostic Injections and Infusions subsection of the Medicine section to describe counseling and administration of the new respiratory syncytial virus (RSV) monoclonal antibody product represented by codes 90380 and 90381. Given the need to have these administration codes in place for the upcoming RSV season, the codes were released early to the American Medical Association (AMA) website and effective as of October 6, 2023. This coding...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article explains a November 2023 CPT coding update focused on administration of respiratory syncytial virus (RSV) monoclonal antibody prophylaxis. It is relevant to professional coders, pediatric practices, and clinicians who report immunization-related services for infants and young children during RSV season. The brief summarizes the new CPT administration codes, discusses their relationship to the associated product codes, and includes general coding guidance and example scenarios.

Why This Topic Matters

The update affects how RSV preventive services are reported in CPT and may influence billing workflows for pediatric immunization encounters during RSV season. It is especially important for practices that provide counseling before administration and those that document administration-only visits.

Article Sections

  1. November 2023 page 15

    Introductory publication context for the coding brief and the topic covered in the article.

  2. Therapeutic, Prophylactic, and Diagnostic Injections and Infusions

    Overview of the CPT medicine subsection where the new administration guidance is located and the general category of service addressed.

  3. Clinical Example and Description of Procedure

    Typical pediatric scenarios illustrating the counseling-based and administration-only situations discussed in the brief.

What You Will Learn

  • How the article frames the new CPT update for RSV preventive administration services.
  • What general setting and specialty area the new guidance applies to.
  • Which types of documentation scenarios are discussed for the administration services.
  • How the article connects the administration guidance to related product coding.
  • What kinds of reference material and example scenarios are included in the brief.

Who Should Read This

  • Medical coders
  • Billing staff
  • Pediatric practices
  • Clinicians documenting immunization services
  • Revenue cycle teams

Codes Discussed


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