Pathology and Laboratory: Molecular Pathology (Q&A) (August 2017)

August 2017 page 10 Pathology and Laboratory: Molecular Pathology Question: A patient had a thromboembolic event and was placed on a newer oral anticoagulant (eg, dabigatran, rivaroxaban). The physician wishes to evaluate the patient for venous thrombophilia risk factors. The new oral anticoagulants interfere with these assays and may cause false positive results. Therefore, an "in vitro" neutralization method is used to eliminate interference to obtain accurate thrombophilia assessments so that the patient does not need to discontinue treatment. Is it appropriate to report code 85525, Heparin neutralization, for assays that eliminate interference from other anticoagulants, as this is...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article addresses a molecular pathology coding question involving laboratory assay interference from newer oral anticoagulants and the general approach to reporting a neutralization method when a dedicated CPT code is not available. It is relevant to pathology and laboratory coding professionals, especially those working with hematology and coagulation testing. The discussion focuses on code selection, the role of unlisted reporting, and documentation support for the claim.

Why This Topic Matters

Laboratory methods that remove test interference can affect how procedures are reported for reimbursement and claim support. Understanding the scope of available coding options helps coders and billers apply CPT guidance consistently in specialized coagulation testing scenarios.

Article Sections

  1. August 2017 page 10

    A brief question-and-answer discussion on molecular pathology and laboratory reporting in a coagulation testing context.

What You Will Learn

  • How the article frames a laboratory assay interference scenario in coagulation testing.
  • What general CPT reporting issue is raised when no dedicated code is available.
  • What types of documentation support are discussed for unlisted procedure reporting.
  • How the article situates the topic within pathology and laboratory coding guidance.

Who Should Read This

  • Pathology and laboratory coders
  • Medical billers
  • Compliance staff
  • Hematology/coagulation laboratory professionals
  • Coding educators

Codes Discussed


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