AMA CPT® Assistant - 2021 Issue 3 (March)

Reporting Intrathecal Injection of Nusinersen (March 2021)

March 2021 page 3 Reporting Intrathecal Injection of Nusinersen Over the past several years, numerous inquiries have been received via the American Medical Association’s (AMA’s) Current Procedural Terminology (CPT®) Network regarding appropriate reporting of intrathecal injections of nusinersen, a complex biological drug used to treat spinal muscular atrophy (SMA). This article discusses the appropriate coding and reporting of this service. Use of Nusinersen for Patients With SMA SMA patients have a genetically defective or missing SMN1 gene, which is responsible for the majority of survival motor neuron (SMN) protein production and is necessary to prevent neuron cell death...

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CPT® Assistant content is the official source for CPT® coding guidance. It is an instrumental tool when appealing insurance denials and validating coding to auditors. Monthly issues and an extensive archive provide comprehensive guidance on proper CPT® coding for past, present and upcoming code set releases. Archives date back to 1990 for historical use of codes, changes, rationales, coding tips and trends in the industry.

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