Article Overview

This article covers CPT coding guidance for Her2-neu FISH analysis performed on tissue and cytologic specimens. It explains the general scope of in situ hybridization reporting, notes the CPT revision history relevant to the laboratory codes discussed, and describes the distinction between qualitative and quantitative or semi-quantitative testing methods. The content is aimed at coders, billing staff, and pathology/laboratory personnel who need to understand which coding framework applies to these types of specimens and analysis methods.