CPT® Code Modifiers

-/+ Deleted, Replaced, Expanded Codes

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Genetic Testing Code Modifiers

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Neoplasia (Solid Tumor, Excluding Sarcoma and Lymphoma)

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0A BRCA1 (hereditary breast/ovarian cancer)
0B BRCA2 (hereditary breast cancer)
0C Neurofibromin (neurofibromatosis, type 1)
0D Merlin (neurofibromatosis, type 2)
0E c-RET (multiple endocrine neoplasia, types 2A/B, familial medullary thyroid carcinoma)
0F VHL (Von Hippel Lindau disease, renal carcinoma)
0G SDHD (hereditary paraganglioma)
0H SDHB (hereditary paraganglioma)
0I ERRB2, commonly called Her-2/neu
0J MLH1 (HNPCC, mismatch repair genes)
0K MSH2, MSH6, or PMS2 (HNPCC, mismatch repair genes)
0L APC (hereditary polyposis coli)
0M Rb (retinoblastoma)
0N TP53, commonly called p53
0O PTEN (Cowden's syndrome)
0P KIT, also called CD117 (gastrointestinal stromal tumor)
0Z Solid tumor gene, not otherwise specified
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