Neutropenic Colitis

A 61-year-old male with acute monocytic leukemia was admitted with fatigue, fever, chills, night sweats, leg pain, weight loss and shortness of breath. CT scan demonstrated signs of descending and sigmoid colon typhlitis, and the provider’s final diagnostic statement listed, “Neutropenic colitis, likely chemotherapy induced acute colitis.” When referencing the Index to Diseases under Typhlitis, the classification directs the coding professional to appendicitis; however, the provider disagreed and stated that typhlitis is inflammation of the colon. What is the correct code assignment for descending and sigmoid colon typhlitis? ...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article addresses a coding scenario involving neutropenic colitis in a patient with leukemia and chemotherapy-related illness. It explains the relevance of diagnosis classification guidance, the role of provider documentation, and the general considerations used when determining the appropriate diagnosis code for a colon inflammatory condition in the setting of neutropenia.

Why This Topic Matters

It helps coders and auditors understand how to approach a complex diagnosis query where documentation, clinical context, and indexed terminology may not align cleanly. The topic is relevant to inpatient coding, oncology-related complications, and diagnosis coding review workflows.

What You Will Learn

  • How a neutropenic colitis coding question is framed in a clinical scenario
  • Why provider documentation matters in classification of a colon inflammatory diagnosis
  • How chemotherapy context can affect the coding review process at a high level
  • How index references and clinical statements may be considered when researching a diagnosis

Who Should Read This

  • Medical coders
  • Coding auditors
  • Clinical documentation improvement specialists
  • Inpatient coding professionals
  • Oncology coding staff

Codes Discussed

  • ICD-10-CM: K52.89

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