Immunology Updates in CPT 2022 (March 2022)

March 2022 page 11 Immunology Updates in CPT 2022 For the Current Procedural Terminology (CPT®) 2022 code set, many updates were made in the Pathology and Laboratory section, which was expanded to accommodate more than four dozen new codes. This article provides an overview of the changes in the Immunology subsection by reviewing three new codes (86231, 86258, 86364) that were established to report specific antibody testing associated with celiac disease. Immunology  86231Endomysial antibody (EMA), each immunoglobulin (Ig) class  86258Gliadin (deamidated) (DGP) antibody, each immunoglobulin (Ig) class  86364Tissue transglutaminase, each immunoglobulin (Ig) class Celiac disease is a chronic...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article explains a small set of CPT 2022 immunology changes within the Pathology and Laboratory section, centered on antibody testing related to celiac disease. It is useful for coding professionals, laboratory staff, and clinicians who need to understand what changed in the immunology subsection and how the update fits into broader reporting practices. The article includes a high-level discussion of the affected testing area, references to prior method-based reporting, and clinical example sections tied to the new codes.

Why This Topic Matters

It helps readers identify whether the CPT 2022 immunology update affects celiac-related laboratory reporting and understand the general context of the revision.

Article Sections

  1. March 2022 page 11

    Publication and page reference information for the CPT Assistant update.

  2. Immunology

    An overview of the immunology subsection changes in CPT 2022, with focus on celiac-disease-related laboratory testing.

  3. Clinical Example and Description of Procedure for 86231

    A clinical scenario and procedural discussion associated with one of the new celiac-related antibody testing codes.

  4. Clinical Example and Description of Procedure for 86258

    A clinical scenario and procedural discussion associated with one of the new celiac-related antibody testing codes.

  5. Clinical Example and Description of Procedure for 86364

    A clinical scenario and procedural discussion associated with one of the new celiac-related antibody testing codes.

What You Will Learn

  • How the CPT 2022 immunology update is framed within the Pathology and Laboratory section
  • Which general area of laboratory testing is affected by the new celiac-related codes
  • How the article situates the new codes in relation to prior method-based reporting
  • What kinds of clinical examples accompany the update

Who Should Read This

  • Medical coders
  • Laboratory billing staff
  • Pathology and laboratory personnel
  • Clinicians involved in celiac-related testing
  • Revenue cycle professionals

Codes Discussed


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