New Monkeypox Testing and Vaccine Codes: July Update (July Special Update (Monkeypox) 2022)

July Special Update (Monkeypox) 2022 page 1 New Monkeypox Testing and Vaccine Codes: July Update In response to the emergent nature of the public health concern surrounding monkeypox, the Current Procedural Terminology (CPT®) Editorial Panel (the Panel) has approved three new codes specific to monkeypox. The Panel approved one code (87593) to report the laboratory diagnostic testing for the orthopoxvirus and two new vaccine product codes (90611, 90622) for the smallpox and monkeypox combined vaccine (JYNNEOS) and the traditional smallpox vaccine (ACAM2000), respectively. The AMA expedited publication of these new codes to the AMA website at https://www.ama-assn...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This CPT® Assistant special update explains newly issued monkeypox-related coding guidance and why it matters for laboratories, vaccinators, and billing teams tracking orthopoxvirus testing and vaccine services. It discusses the affected CPT code set, the associated vaccine administration codes, and practical context from public health and FDA sources. The article also includes clinical examples and procedure descriptions to illustrate the general reporting scenarios covered by the update.

Why This Topic Matters

The update is relevant to professionals who need to recognize newly introduced monkeypox-related CPT codes and understand the surrounding guidance for testing and vaccine services. It helps readers identify which parts of the CPT code set were affected and what general topics the accompanying article addresses.

Article Sections

  1. July Special Update (Monkeypox) 2022 page 1

    Introduces the special update and summarizes the new monkeypox-related CPT additions, including testing and vaccine product codes. It also notes the broader CPT publication context and references to external public health guidance.

  2. Microbiology

    Covers the laboratory testing portion of the update and places the new testing code within the microbiology area of CPT. The section also discusses the public health context for reporting and tracking testing services.

  3. Vaccines, Toxoids

    Covers the vaccine product portion of the update and places the new vaccine codes within the vaccines and toxoids area of CPT. The section also discusses general vaccination context, product background, and related public health references.

  4. Clinical Example (87593) / Description of Procedure (87593)

    Provides a representative scenario and associated procedure narrative for the laboratory testing code. It shows the kind of clinical context addressed in the article without substituting for the full guidance.

  5. Clinical Example (90611) / Description of Procedure (90611)

    Provides a representative scenario and associated procedure narrative for one of the vaccine product codes. The section illustrates the general type of encounter discussed in the update.

  6. Clinical Example (90622) / Description of Procedure (90622)

    Provides a representative scenario and associated procedure narrative for the other vaccine product code. The section illustrates the general type of encounter discussed in the update.

What You Will Learn

  • What new monkeypox-related CPT guidance was issued in the update
  • Which broad CPT areas the new testing and vaccine codes relate to
  • How the article frames the surrounding public health and FDA context
  • What types of clinical scenarios the article uses to illustrate the new guidance

Who Should Read This

  • Medical coders
  • Billing and reimbursement staff
  • Clinical laboratory personnel
  • Vaccination program staff
  • Compliance and revenue cycle teams

Codes Discussed


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