AMA CPT® Assistant - 2014 Issue 6 (June)
Pathology and Laboratory: Surgical Pathology (Q&A) (June 2014)
June 2014 page 15 Pathology and Laboratory: Surgical Pathology Question: What is the appropriate CPT code to capture epidermal nerve fiber density testing on skin biopsies? Answer: Epidermal nerve fiber density testing (also referred to as intraepidermal nerve fiber [IENF] density) involves special histologic evaluation of skin biopsies utilizing quantitative immunohistochemistry for neural elements (ie, panaxonal marker, anti-protein gene product 9.5). The physician identifies and reports the number of intraepidermal nerve fibers per linear millimeter of epidermis. This report is used in the assessment of sensory neuropathies seen in diabetes mellitus and cancer chemotherapy, as well as idiopathic...
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