Pathology and Laboratory: Surgical Pathology (October 2010)

October 2010 page 3b Pathology and Laboratory: Surgical Pathology Question: We received two blocks, both labeled ABC09-1234 C&D. We perform immunoperoxidase CD20 and CD45 on both blocks. Would we code this scenario as 88342 x 2 or 88342 x 4? Answer: CPT code 88342, Immunohistochemistry (including tissue immunoperoxidase), each antibody, should be reported twice. It is “each antibody” no matter how many blocks are applied to a given specimen. Pathology and Laboratory: Surgical Pathology (October 2010). CPT® Assistant. 2010; October 2010 page 3b ...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This short CPT Assistant article focuses on a pathology and laboratory billing question in surgical pathology. It is intended for coders and billing staff who work with pathology services and need to understand the general topic of how the article addresses reporting for immunohistochemistry in relation to specimen blocks. The piece is concise and narrowly scoped, with the discussion centered on a single scenario rather than a broad policy update.

Why This Topic Matters

Articles like this help coders interpret CPT guidance for pathology services and determine whether a particular workflow falls within the scope of the premium discussion.

What You Will Learn

  • The article’s focus within surgical pathology coding
  • How the discussion is framed around immunohistochemistry reporting
  • The limited billing scenario addressed by the CPT Assistant question-and-answer format
  • Why the article is relevant to pathology coding workflows

Who Should Read This

  • Pathology coders
  • Laboratory billing staff
  • Compliance professionals
  • Revenue cycle teams

Codes Discussed


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Welcome to the ultimate resource for mastering CPT coding – the CPT® Assistant. This indispensable tool, brought to you by the American Medical Association (AMA), is designed specifically for medical coders, auditors, and billers who strive for accuracy and efficiency in their daily work with patient charts. Whether you are validating codes, training staff, or appealing insurance denials, CPT Assistant provides the authoritative guidance you need to excel.

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With CPT Assistant, you can navigate the complexities of medical coding with unparalleled confidence. This resource offers authoritative answers and expert explanations that help reduce coding errors, leading to fewer claim denials and streamlined appeals processes. The comprehensive archive of articles, updated monthly, ensures you always have the most current information at your fingertips, enhancing your ability to stay ahead of industry changes and trends.

CPT Assistant’s visual aids, such as anatomical illustrations and procedural charts, make complex codes easier to understand, improving your accuracy and efficiency. By integrating this resource into your daily workflow, you can save valuable time and enhance your productivity.

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