AMA CPT® Assistant - 2025 Issue 12 (December)
Reporting IRE Tumor Ablation (47384, 55877)
December 2025 page 12 Reporting IRE Tumor Ablation (47384, 55877) For the CPT 2026 code set, two new Category I codes (47384, 55877) have been established to report percutaneous irreversible electroporation (IRE) tumor ablation with imaging guidance of the liver (47384) and the prostate (55877). As a result of the creation of these two new Category I codes, Category III code 0600T has been revised. This article provides an overview of these changes. Digestive System Liver 47384 Ablation, irreversible electroporation, liver, 1 or more tumors, including imaging guidance, percutaneous (Do not report 47384 in conjunction with 76940, 77002, 77013...
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Article Overview
This article explains CPT 2026 reporting changes for percutaneous irreversible electroporation tumor ablation. It is relevant to coders, billers, and clinical documentation teams working with digestive system, male genital system, and interventional oncology procedures. The discussion covers the addition of new organ-specific reporting, related revisions to an existing Category III code, and the surrounding guidance that affects how these procedures are categorized in the code set.
Why This Topic Matters
Coding for irreversible electroporation is changing in CPT 2026, and the article helps readers understand how the new structure affects documentation review, code lookup, and interpretation of related parenthetical guidance.
Article Sections
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December 2025 page 12
Publication metadata and article placement information.
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Digestive System
Coverage of the CPT update related to liver procedures within the digestive system.
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Male Genital System
Coverage of the CPT update related to prostate procedures within the male genital system.
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Category III Codes
Discussion of the revised Category III reporting structure and its relationship to the new CPT codes.
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Clinical Example (47384)
Representative liver-related clinical scenarios and procedural illustration associated with the new reporting guidance.
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Description of Procedure (55877)
Representative prostate-related procedural illustration associated with the new reporting guidance.
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Clinical Example (0600T)
Representative clinical scenario and procedural illustration associated with the Category III code.
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Description of Procedure (0600T)
Procedural illustration associated with the Category III code and its broader anatomic scope.
What You Will Learn
- What CPT 2026 changes are described for irreversible electroporation tumor ablation
- How the article organizes reporting by anatomic site and code family
- What kinds of parenthetical guidance are discussed alongside the new and revised codes
- How the article uses clinical examples and procedure descriptions to illustrate reporting scenarios
Who Should Read This
- Medical coders
- Coding auditors
- Billing staff
- Clinical documentation improvement professionals
- Interventional radiology and oncology practices
Codes Discussed
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